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Constipation Clinical Research

Learn about Achieve's Constipation Clinical Trial
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Toilet roll for someone with constipationDo you want to know why we conduct clinical trials for constipation? This is a condition which affects almost everyone from time to time. Fortunately, most cases are very mild and don’t require any treatment. Clinical trials, like the ones we conduct here in Birmingham, allow experts to test new treatments which could aid people suffering from chronic cases of constipation.

As you could imagine, constipation is not exactly the most popular topic of conversation. Yet it’s something most of us have or will deal with at least once during our lifetimes. People who routinely struggle with the symptoms of constipation know that they can be both exasperating and painful. Taking steps to prevent constipation become even more important as we age.

Constipated Fast Facts

  • Bowel movement (BM’s) regularity varies from person to person, so going a few days without one doesn’t necessarily mean you’re constipated.
  • Constipation is classified as having less than three BM’s per week.
  • Having less than one BM per week means you’re severely constipated.
  • Chronic constipation could be a sign of some more serious underlying issue.
  • Dairy can cause constipation if you are lactose intolerant.

Being constipated means that bowel movements have become less frequent, or stool is more difficult to pass. Bowel movement regularity can vary greatly from person to person. Some people normally go three times or more a day, while others only go a few times a week. As a general rule, three days should not pass without at least one BM. The stool will become harder and more difficult to pass after three days.

If you’re concerned whether you have been constipated lately, here are some questions to ask yourself:

  • Do you find yourself straining during a BM more than 25 percent of the time?
  • Are your stools noticeably hard more than 25 percent of the time?
  • Do you experience the sensation of an incomplete evacuation more than 25 percent of the time?
  • Are you going less than three times a week?

Common Causes of Constipation

Clinical studies have shown that the root cause of a person’s constipation is usually a bowel function issue (rather than say a structural complication). Most contemporary treatments and therapies have been designed with this knowledge in mind. Some of the most common causes of constipation include:

  • A fiber-deficient diet
  • Dehydration
  • Travel or other disruptions in normal dieting routines
  • Low levels of physical activity
  • Eating too much dairy products
  • High levels of stress
  • Over-dependence on laxatives, which have been shown to weaken the muscles of the bowels overtime
  • Hypothyroidism
  • Certain over-the-counter medicines for acid reflux (ones containing aluminum or calcium)
  • Fighting the urge to go (often because of a hemorrhoid)
  • Prescription painkillers or some antidepressants (check out this article for more information)
  • Certain eating disorders
  • Pregnancy
  • Depression
  • Irritable bowel syndrome (IBS)
  • Certain neurological illnesses such as multiple sclerosis or Parkinson’s disease
  • Could also be a symptom of colon cancer

Research has also shown that some people develop chronic constipation as a result of poor nerve and muscle function in their bowels. This is more rare, but something that should be kept in mind.

Anyone who is interested in our constipation clinical trial should know that their level of participation does not have to be a very demanding experience. Participating in a clinical trial in Birmingham, AL may only require agreeing to let our researchers have a copy of your test results– most will require a little more involvement than that.

All participants will be compensated for time and travel, and any study related care. The following are all provided free of charge:

  • Physical examinations
  • Laboratory services
  • Study related medication

Read more posts about Constipation on the Achieve Clinical Blog

Constipation Research Clinical Trials in Birmingham, AL

Achieve Clinical Research is currently conducting a wide array of clinical studies targeted towards certain conditions. You may be eligible to participate in one of our constipation clinical trials and contribute to the development and approval of a new drug or treatment. As a participant, there is no cost to you at any point during the study and health insurance is not required. Browse our clinical trials being conducted now to find the study best suited for you.

An Educational Video on the Causes of Constipation

 

Additional Resources for Patients with Constipation

MedlinePlus – NIH

World Gastroenterology Organization

American Gastroenterological Association

American College of Gastroenterology

If you live around Central Alabama, click here to learn more about participating in a constipation clinical trial. Also, our sister site Avail Clinical Research conducts constipation clinical trials in DeLand, Florida.