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Hypogonadism Clinical Research

Learn about Achieve's Hypogonadism Clinical Trials


Man screened for a hypogonadism clinical trial in Birmingham, AlabamaHypogonadism is a chronic disorder with a wide array of symptoms that can be managed with appropriate medical treatment. However, a comprehensive cure for this condition has yet to be discovered. Lifelong treatment is often required and if treatment is stopped, symptoms can begin to resurface. This is why we are conducting hypogonadism clinical research in Birmingham, Alabama to find new and more effective treatment methods.

Interested in learning more about hypogonadism clinical research? You can fill out the form in the right hand corner of this page. A member of our staff will then contact you to discuss active research studies and your eligibility for enrollment. You can also call us at (205) 757-8208 to speak with one of our experts about upcoming hypogonadism clinical studies in Birmingham, Alabama.

What Exactly is Hypogonadism?

Hypogonadism is a condition that can afflict both men and women where the sex glands produce little to no sex hormones. Also known as the gonads, the sex glands primarily responsible for producing sex hormones are the ovaries in women and the testes in men.

Sex hormones have a variety of important functions in the sexual development of both men and women. In men, sex hormones help control testicular development and pubic hair growth, as well as sperm production. In women, sex hormones are responsible for helping with pubic hair growth, breast development and play a role in the menstrual cycle.

There are two types of hypogonadism people can suffer from. The first is primary hypogonadism. A condition that occurs when the brain is sending the appropriate signals to the gonads to produce sex hormones, but due to an issue with the gonads, they are unable to produce the necessary hormones.

The second type of hypogonadism is called central hypogonadism or secondary hypogonadism. This condition occurs when there is a problem with the area of your brain responsible for controlling the gonads. These sections of the brain are known as the hypothalamus and the pituitary gland.

Men might experience the following symptoms from hypogonadism:

  • Muscle loss
  • Low labido
  • Osteoporosis
  • Erectile dysfunction
  • Reduced growth of penis and testicles
  • Breast enlargement
  • Loss of body hair
  • Infertility

In women the symptoms of hypogonadism include:

  • Energy and mood changes
  • Body hair loss
  • Slow or absent breast growth
  • Hot flashes
  • Menstruation stops
  • Lack of sex drive

What Causes Hypogonadism?

The causes of hypogonadism can differ depending on the type of hypogonadism you have, either primary or central hypogonadism. With primary hypogonadism, where the issues originate from a problem with the testes or ovaries, the causes include:

  • Infection
  • Liver and kidney diseases
  • Undescended testes
  • Radiation
  • Autoimmune disorders
  • Surgery
  • Developmental and genetic disorders, most commonly Turner Syndrome or Klinefelter Syndrome

If you have central hypogonadism, the problems stem from the hypothalamus and pituitary gland in your brain not functioning properly. This can be caused by:

  • Nutritional deficiencies
  • Infections
  • Radiation
  • Tumors
  • Trauma
  • Genetic Disorders
  • Surgery
  • Rapid and severe weight loss
  • Long-term use of steroids
  • Pituitary disorders
  • Hemochromatosis
  • Inflammatory diseases
  • Certain medicines, such as glucocorticoids and opiates

An Educational Video on Hypogonadism

Hypogonadism Treatment & Hormone Therapy

Hypogonadism treatments will differ depending on your sex and the originating cause of the condition. Most treatment methods involve some form of hormone therapy to help balance the changes in hormone levels caused by this condition.

For women estrogen is commonly used for hormone therapy. Estrogen can be introduced to the body through several methods including:

  • Injection
  • Pills
  • Skin Patch

Unfortunately, this process can increase the risk of endometrial cancer. To combat this increased risk, progesterone is usually combined with estrogen treatments.

To treat men suffering from hypogonadism, the hormone testosterone is most commonly used. As with estrogen, testosterone can be introduced into the body through a few different practices:

  • Pills
  • Administering a solution to the armpit
  • Specially formulated lozenge
  • Skin gel
  • Skin patch

In the event of a tumor in the brain being the root cause of hypogonadism, treatment will be directed towards getting rid of the tumor. Methods for stopping the tumor growth or completely removing it may involve:

  • Surgery
  • Radiation
  • Medication

Hypogonadism Clinical Research Studies in Birmingham, AL

If you would like to take part in a hypogonadism clinical research study, our team will help you get started. Hopefully, you’ve taken a few seconds to fill out our online form– it’s a great way to connect with on of our clinical trial experts. We also recommend that you spend some time checking out our resource sections for participants.

Man is happy after completing a hypogonadism clinical study in Birmingham, Alabama

As a participant, there is no cost to you at any point during the study and health insurance is not required. Participants may also receive compensation for completing a research study at Achieve Clinical Research.

If you are not eligible for one of our hypogonadism clinical trials, there are other conditional studies you might qualify for. Call us today at (205) 757-8208 and our research team will find the most appropriate study to enroll you in.

Additional Resources for Hypogonadism